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CVB Financial, ClickSoftware Technologies and BioDelivery Sciences International lead small-cap in pre-market

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CVB Financial Corp. (Nasdaq:CVBF), ClickSoftware Technologies Ltd. (Nasdaq:CKSW) and BioDelivery Sciences International Inc. (Nasdaq:BDSI) are among the most actively traded small-cap companies in Wednesday's trading among companies with market capitalizations under $1 billion.

Also included among the results: Fuqi International Inc. (Nasdaq:FUQI), Spectrum Pharmaceuticals Inc. (Nasdaq:SPPI), Biocryst Pharmaceuticals Inc. (Nasdaq:BCRX), Spartan Motors Inc. (Nasdaq:SPAR), Geron Corp. (Nasdaq:GERN) and A Power Energy Generation Systems Ltd. (Nasdaq:APWR).

Here are the biggest percentage losers among small caps:

    Price at 9:08 ET Change % Change Volume Year High Year Low
CVBF CVB FINL CORP   6.25     -0.01     -0.2%     702.1k     20.00     4.91  
CKSW CLICKSOFTWARE TECHNOLOGIES L   7.30     +0.56     +8.3%     77.7k     7.45     1.80  
BDSI BIODELIVERY SCIENCES INTL IN   5.68     +0.38     +7.2%     66.1k     8.29     1.93  
FUQI FUQI INTERNATIONAL INC   22.17     -1.36     -5.8%     45.8k     24.00     3.31  
SPPI SPECTRUM PHARMACEUTICALS INC   6.64     +0.05     +0.8%     28.5k     8.15     0.55  
BCRX BIOCRYST PHARMACEUTICALS   7.47     -0.11     -1.5%     18.0k     7.92     0.85  
SPAR SPARTAN MTRS INC   9.99     +0.48     +5.0%     17.5k     11.75     1.31  
GERN GERON CORP   7.70     -0.09     -1.2%     14.2k     8.50     1.95  
APWR A POWER ENERGY GENERAT SYS L   9.25     -0.19     -2.0%     12.1k     28.68     3.00  
OREX OREXIGEN THERAPEUTICS INC   7.50     -0.02     -0.3%     11.8k     12.28     1.55