Pre-market: Sirtris Pharmaceuticals, P.F. Chang's China Bistro and Anadigics lead small-cap volume
Sirtris Pharmaceuticals Inc. (Nasdaq:SIRT), P.F. Chang's China Bistro (Nasdaq:PFCB) and Anadigics, Inc. (Nasdaq:ANAD) are among the most actively traded companies in Wednesday's pre-market trading among those with market capitalizations under $750 million.
YRC Worldwide Inc. (Nasdaq:YRCW), Packeteer, Inc. (Nasdaq:PKTR) and FuelCell Energy, Inc. (Nasdaq:FCEL) are also among the most actively traded small-cap companies in pre-market trading.
Here are the most actively traded small-cap companies in Wednesday's pre-market trading:
| Price at 9:06 ET | Change | % Change | Volume | Year High | Year Low |


















