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Pre-market: Sirtris Pharmaceuticals, P.F. Chang's China Bistro and Anadigics lead small-cap volume

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Sirtris Pharmaceuticals Inc. (Nasdaq:SIRT), P.F. Chang's China Bistro (Nasdaq:PFCB) and Anadigics, Inc. (Nasdaq:ANAD) are among the most actively traded companies in Wednesday's pre-market trading among those with market capitalizations under $750 million.

YRC Worldwide Inc. (Nasdaq:YRCW), Packeteer, Inc. (Nasdaq:PKTR) and FuelCell Energy, Inc. (Nasdaq:FCEL) are also among the most actively traded small-cap companies in pre-market trading.

Here are the most actively traded small-cap companies in Wednesday's pre-market trading:

    Price at 9:06 ET Change % Change Volume Year High Year Low
 SIRT  SIRTRIS PHARMACEUTICALS INC   22.20     +9.97     +81.5%     617.9k     21.99     9.50  
 PFCB  P F CHANGS CHINA BISTRO INC   32.62     +2.10     +6.9%     128.8k     42.97     20.41  
 ANAD  ANADIGICS INC   10.25     +1.92     +23.0%     126.5k     19.53     5.85  
 YRCW  YRC WORLDWIDE INC   12.81     -0.19     -1.5%     81.5k     45.99     10.99  
 PKTR  PACKETEER INC   6.96     +0.00     +0.0%     50.8k     10.52     3.81  
 FCEL  FUELCELL ENERGY INC   8.90     +0.94     +11.8%     43.7k     13.14     5.43  
 CSGS  CSG SYS INTL INC   12.00     +0.15     +1.3%     42.4k     28.22     10.49  
 MCBC  MACATAWA BK CORP   10.29     +0.00     +0.0%     41.1k     16.44     7.56  
 FEED  AGFEED INDUSTRIES INC   19.70     -0.49     -2.4%     36.8k     20.38     5.15  
 CYMI  CYMER INC   28.00     +3.68     +15.1%     19.0k     44.73     22.86