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Vital Images, Inc. leads Wednesday small-cap pre-market volume

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Medical imaging company Vital Images, Inc. (Nasdaq: VTAL) revealed disappointing second-quarter preliminary results and cut its annual revenue guidance.

Biopharmaceutical company Novacea, Inc. (Nasdaq: NOVC) reported a $60 million deal with healthcare company Schering-Plough Corp. (NYSE: SGP) for the development and commercialization for Novacea’s cancer drug Asentar.

The following are the most actively traded companies in Wednesday pre-market trading among those with market capitalizations under $500 million:

    Price at %
9:07 et Change Change Volume Year High Year Low
 VTAL  VITAL IMAGES INC   20.47     -6.00     -22.7%     336.5k     36.67     19.52  
 NOVC  NOVACEA INC   10.11     +0.60     +6.3%     136.9k     17.25     5.45  
 LOCM  LOCAL COM CORP   9.19     +0.32     +3.6%     99.7k     13.74     3.05  
 TRCA  TERCICA INC   6.20     +0.78     +14.4%     54.5k     7.43     4.12  
 JSDA  JONES SODA CO   17.50     -0.43     -2.4%     43.8k     32.60     7.51  
 HOKU  HOKU SCIENTIFIC INC   12.22     +0.21     +1.7%     39.6k     12.97     2.12  
 ASYS  AMTECH SYS INC   10.86     +0.86     +8.6%     24.5k     10.50     5.95  
 IMMR  IMMERSION CORP   18.95     +0.66     +3.6%     17.6k     18.73     5.03  
 PNNT  PENNANTPARK INVT CORP   10.05     -4.28     -29.9%     10.0k     15.20     14.00  
 SGMO  SANGAMO BIOSCIENCES INC   9.01     +0.46     +5.4%     8.6k     8.89     4.26